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HRID1632343

反应详情

EQUATION

反应方程式

HRID 1632343 的结构方程式

REACTANTS

反应物

3
结构：CO
HCID887

Methanol

CH4O

2 次

结构：C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
HCID222528

Deoxycholic acid

C24H40O4

结构：N[C@H]1CC[C@H](O)C1
HCID42614395

(1S,3S)-3-Aminocyclopentan-1-ol

C5H11NO

PRODUCTS

生成物

1
结构：C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.N[C@@H]1C=CC[C@H]1O
HCID12943949

未命名化合物

PROCEDURE

实验过程

A 49.5 g (0.50 M) quantity of dl trans-3-amino-hydroxycyclopentane dissolved in about 100-200 ml of methanol and 98 g (0.25M) of deoxycholic acid dissolved in about 200-300 ml of methanol are mixed and allowed to crystallize for several hours. The crystals of trans-3-amino-4-hydroxycyclopentene are collected by filtration and washed three times with some portions of methanol. There is obtained 105 g of trans-3-amino-4-hydroxycyclopentene deoxycholate as light beige crystals, m.p. 195°-197° (dec). The mother liquors are saved for Step 2.

WORKUP

后处理

  1. additionare mixed
  2. customto crystallize for several hours
  3. filtrationThe crystals of trans-3-amino-4-hydroxycyclopentene are collected by filtration
  4. washwashed three times with some portions of methanol