Hydrochloric Acid → H-Ser-Ser-OMe.HCl

HRID 1632427Notes

Reaction equation

HRID 1632427 reaction equation
[NH:1](C(OCC1C=CC=CC=1)=O)[C@H:2]([C:5]([NH:7][C@H:8]([C:11]([O:13][CH3:14])=[O:12])[CH2:9][OH:10])=[O:6])[CH2:3][OH:4].[H][H].[ClH:27]>CO.[Pd]>[NH2:1][C@H:2]([C:5]([NH:7][C@H:8]([C:11]([O:13][CH3:14])=[O:12])[CH2:9][OH:10])=[O:6])[CH2:3][OH:4].[ClH:27]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 11809968Z-Ser-Ser-OmeHCID 178418361HCID 178418361, compound

Product 1

HCID 131713879H-Ser-Ser-OMe.HCl

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

2.5 Grams of Z-Ser-Ser-OMe was dissolved in 50 ml of methanol with 7.34 ml of 1N-hydrochloric acid, then in the presence of 500 mg of palladium balck, catalytic reduction was carried out at 20° C., under 1 atmospheric pressure of hydrogen gas, to obtain H-Ser-Ser-OMe.HCl.

Sources & evidence

ORD record
ord-10d24d62a4b84c408535673d00e716d2
Source dataset
uspto-grants-1984_10
Patent number
US04474754

Reaction notes

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