Hydrazine hydrate (1:1) → HCID 131713885, compound

HRID 1632432Notes

Reaction equation

HRID 1632432 reaction equation
[NH:1]([C:32]([O:34][CH2:35][C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)=[O:33])[C@H:2]([C:11]([NH:13][C@H:14]([C:19]([NH:21][C@H:22]([C:27](OCC)=[O:28])[CH2:23][CH:24]([CH3:26])[CH3:25])=[O:20])[CH2:15][C:16](=[O:18])[NH2:17])=[O:12])[CH2:3][C:4]1[CH:9]=[CH:8][C:7](O)=[CH:6][CH:5]=1.[OH2:42].[NH2:43][NH2:44]>CO>[NH:1]([C:32]([O:34][CH2:35][C:36]1[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=1)=[O:33])[C@H:2]([C:11]([NH:13][C@H:14]([C:19]([NH:21][C@H:22]([C:27]([NH:43][NH2:44])=[O:28])[CH2:23][CH:24]([CH3:26])[CH3:25])=[O:20])[CH2:15][C:16](=[O:18])[NH2:17])=[O:12])[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([OH:42])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 131713886HCID 131713886, compound

Product 1

HCID 131713885HCID 131713885, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2.78 Grams of Z-Tyr-Asn-Leu-OEt was dissolved in 30 ml of methanol, further 1.21 ml of hydrazine hydrate was added to the solution and the mixture was allowed to stand overnight, the crystals formed were collected by filtration, then washed with a small amount of methanol to obtain 3.10 g of Z-Tyr-Asn-Leu-NHNH2.

Workup

  1. customthe crystals formed
  2. filtrationwere collected by filtration
  3. washwashed with a small amount of methanol

Sources & evidence

ORD record
ord-d6db2011deee46fc9c0e1c692860b975
Source dataset
uspto-grants-1984_10
Patent number
US04474754

Reaction notes

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