Hydrochloric Acid → HCID 13105789, compound

Participants

Reaction Steps

To a solution of Compound 20 (0.85 g) prepared in Example 12 in methanol (100 ml) is added an aqueous solution of sodium hydroxide (10%)(4 ml), and the mixture is stirred for 3 hours, acidified with 10% hydrochloric acid, and concentrated. The residue is washed with water and chloroform to give Compound 21 (0.7 g) in 92% yield.

Provenance & Evidence