Sodium Hydroxide → HCID 23706907, compound

Participants

Reaction Steps

6 g of 4-ethoxy-6-butyryl-7-methylquinoline-2-carboxylic acid ethyl ester are dissolved in 150 ml of ethanol, 9 ml of 2N sodium hydroxide solution are added and the mixture is hydrolysed for 15 minutes at room temperature. The precipitated crystals are filtered with suction and recrystallised from water. Sodium 4-ethoxy-6-butyryl-7-methylquinoline-2-carboxylate having a melting point of above 250° C. is obtained. By dissolving in water and acidifying, 4-ethoxy-6-butyryl-7-methylquinoline-2-carboxylic acid is obtained.

Provenance & Evidence