反应详情

A 4 N hydrochloric acid ethyl acetate solution (20 mL) was added to an ethyl acetate solution (50 mL) of [(1R,2R)-2-hydroxy-1-(3,4,5-trifluorophenyl)propyl]carbamic acid tert-butyl ester (4.49 g). This reaction solution was stirred at room temperature for 5 hr. The reaction solution was concentrated under reduced pressure to give 3.5 g of the title compound. The physical property values of this compound were as follows:

1. concentrationThe reaction solution was concentrated under reduced pressure