反应详情

Pyrrolidine (0.42 ml, 5.0 mmoles) was added to a solution of the title product of Example A3 (0.3 g, 1.0 mmole) in 10 ml of ethanol. The mixture was stirred 3 hours and then allowed to stand for 16 hours at 25°. The reaction mixture was evaporated to dryness in vacuo. The residue was triturated with ether and filtered with pentane wash to yield purified title product, 0.253 g; m.p. 108°-112°.

1. waitto stand for 16 hours at 25°
2. customThe reaction mixture was evaporated to dryness in vacuo
3. customThe residue was triturated with ether
4. filtrationfiltered with pentane
5. washwash
6. customto yield
7. custompurified title product, 0.253 g