3-(Dimethylamino)-2,2-dimethylpropanoic acid hydrochloride → 2,2-Dimethyl-3-dimethylaminopropionyl chloride hydrochloride

HRID 1632738Notes

Reaction equation

HRID 1632738 reaction equation
[ClH:1].[CH3:2][C:3]([CH3:11])([CH2:7][N:8]([CH3:10])[CH3:9])[C:4](O)=[O:5]>S(Cl)(Cl)=O>[ClH:1].[CH3:2][C:3]([CH3:11])([CH2:7][N:8]([CH3:10])[CH3:9])[C:4]([Cl:1])=[O:5]

Participants

3

Reactant 1

HCID 861799163-(Dimethylamino)-2,2-dimethylpropanoic acid hydrochloride

Product 1

HCID 204423692,2-Dimethyl-3-dimethylaminopropionyl chloride hydrochloride

Reagents, catalysts & solvents 1

HCID 24386Thionyl ChlorideSolvent

Procedure

A mixture of 2,2-dimethyl-3-dimethylaminopropionic acid hydrochloride (1.76 g, 0.00969 mole) and thionyl chloride (10 ml) was heated under reflux for 30 minutes.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 30 minutes

Sources & evidence

ORD record
ord-16781f318b4b4f8abc5d0a9299011d39
Source dataset
uspto-grants-1984_10
Patent number
US04477466

Reaction notes

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