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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1632738Generated: October 26, 2026

3-(Dimethylamino)-2,2-dimethylpropanoic acid hydrochloride → 2,2-Dimethyl-3-dimethylaminopropionyl chloride hydrochloride

https://huagongshe.com/reaction/1632738

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Dimethylamino)-2,2-dimethylpropanoic acid hydrochlorideHCID 86179916—
SolventThionyl ChlorideHCID 24386—
Product2,2-Dimethyl-3-dimethylaminopropionyl chloride hydrochlorideHCID 20442369—

Reaction Steps

A mixture of 2,2-dimethyl-3-dimethylaminopropionic acid hydrochloride (1.76 g, 0.00969 mole) and thionyl chloride (10 ml) was heated under reflux for 30 minutes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04477466
Source datasetuspto-grants-1984_10
ORD IDord-16781f318b4b4f8abc5d0a9299011d39
Source noteuspto-grants-1984_10