HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-5-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one → 3-Phthalimido-5-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-5-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one | HCID 20442349 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Phthalimido-5-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one | HCID 20442320 | — |
Reaction Steps
A mixture of 1.05 g of 3-chloro-5-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one and 1.0 of potassium phthalimide is warmed to 90° overnight. The reaction mixture is poured into 20 ml of water and stirring is continued for 1 hr. Isolation and drying affords 3-phthalimido-5-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04477464 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-6b6b42fb61674159b044280a4ef6aaf7 |
| Source note | uspto-grants-1984_10 |