反应详情

A solution of 80 g sodium hydroxide in 200 ml water was added to a mixture of 152 g of vanillin, 95 g chloroacetic acid, and 800 ml water with stirring. The mixture was heated to reflux 65 hours, cooled to room temperature, acidified with 70 ml conc. HCl, and the product collected by filtration. The solid was washed with 2 l of distilled water and dried to give 120 g, 57% yield.

1. temperatureThe mixture was heated
2. temperatureto reflux 65 hours
3. filtrationthe product collected by filtration
4. washThe solid was washed with 2 l of distilled water
5. customdried
6. customto give 120 g, 57% yield