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HRID1632833

反应详情

EQUATION

反应方程式

HRID 1632833 的结构方程式

REACTANTS

反应物

4
结构：NO
HCID787

Hydroxylamine

H3NO

结构：CC(C)(C)NCc1ccccc1
HCID76908

Benzenemethanamine, N-(1,1-dimethylethyl)-

C11H17N

结构：c1ccc(C2OCc3nc(C4CO4)ccc3O2)cc1
HCID13748403

未命名化合物

结构：CC(C)(C)N(Cc1ccccc1)CC(O)c1ccccn1
HCID53930912

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)N(Cc1ccccc1)CC(O)c1ccc2c(n1)COC(c1ccccc1)O2
HCID13340177

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

A solution of 33.0 g. (0.13 mole) 6-(1,2-epoxyethyl)-2-phenyl-4H-1,3-dioxino[5,4-b]pyridine and 22.0 g. (0.135 mole) of N-tert-butylbenzylamine in 200 ml. of methanol was heated to the reflux temperature overnight. Upon cooling there deposited 6-[1-hydroxy-2-(N-tert-butylbenzylamino)ethyl]pyridine which was recrystallized from isopropanol to give 29.4 g. (54%) of the amino alcohol m.p. 126°-130° C.

WORKUP

后处理

  1. customwas recrystallized from isopropanol
  2. customto give 29.4 g