1-Amino-2-propanol → N-(2-chloro-4-(2-hydroxypropylcarbamoyl)phenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide

HRID 163289Notes

Reaction equation

HRID 163289 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][c:10]1[N:11]([C:12](=[O:13])[c:14]1[cH:15][c:16]2[c:17]([s:27]1)-[c:18]1[c:19]([cH:23][cH:24][cH:25][cH:26]1)[O:20][CH2:21][CH2:22]2)[CH3:28].[NH2:29][CH2:30][CH:31]([CH3:32])[OH:33]>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:29][CH2:30][CH:31]([CH3:32])[OH:33])[cH:8][cH:9][c:10]1[N:11]([C:12](=[O:13])[c:14]1[cH:15][c:16]2[c:17]([s:27]1)-[c:18]1[c:19]([cH:23][cH:24][cH:25][cH:26]1)[O:20][CH2:21][CH2:22]2)[CH3:28]

Participants

3

Reactant 2

HCID 41-Amino-2-propanolHCID 668689233-Chloro-4-(N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)benzoic acid

Product 1

HCID 57900244N-(2-chloro-4-(2-hydroxypropylcarbamoyl)phenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide

Sources & evidence

ORD record
ord-b130a0023af144cebcec34d718d72c85
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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