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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1632946Generated: November 2, 2026

Nitrous Acid → 5-Nitroso-8-hydroxyisoquinoline

https://huagongshe.com/reaction/1632946

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitrous AcidHCID 24529—
Reactant8-HydroxyisoquinolineHCID 135441711—
Product5-Nitroso-8-hydroxyisoquinolineHCID 135798744—

Reaction Steps

The 8-hydroxyisoquinoline is reacted with nitrous acid to form 5-nitroso-8-hydroxyisoquinoline. The nitrous acid is generated in situ by the action of mineral acid, such as hydrochloric, sulfuric, and the like, on sodium nitrite usually under cold temperature conditions.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04478820
Source datasetuspto-grants-1984_10
ORD IDord-00cfb305baf9440db3a2eac8175ef501
Source noteuspto-grants-1984_10