Ammonia → HCID 20441522, compound

HRID 1632960Notes

Reaction equation

HRID 1632960 reaction equation
[ClH:1].[C:2]1([C:8]2([C:18]([O:20]CC)=O)[CH2:10][CH:9]2[CH2:11][N:12]2CCOCC2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:23]>>[Cl:1][C:5]1[CH:6]=[CH:7][C:2]([C:8]2([C:18]([NH2:23])=[O:20])[CH2:10][CH:9]2[CH2:11][NH2:12])=[CH:3][CH:4]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 313Hydrochloric Acid2×HCID 13218423HCID 13218423, compound

Product 1

HCID 20441522HCID 20441522, compound

Procedure

In a manner similar to that described in Example 1, but hydrolyzing the hydrochloride of 1-p-chlorophenyl 1-ethoxycarbonyl 2-aminomethyl cyclopropane (Z) and then treating the intermediate acid chloride with ammonia and salifying with hydrochloric acid, there is obtained the product of the formula ##STR16##

Workup

  1. customthere is obtained the product of the formula

Sources & evidence

ORD record
ord-84df9b12e85a4550b7ae703034b8fc37
Source dataset
uspto-grants-1984_10
Patent number
US04478836

Reaction notes

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