Ammonia → HCID 20441518, compound

HRID 1632961Notes

Reaction equation

HRID 1632961 reaction equation
[ClH:1].[C:2]1([C:8]2([C:18]([O:20]CC)=O)[CH2:10][CH:9]2[CH2:11][N:12]2[CH2:17]COC[CH2:13]2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:23]>>[Cl:1][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[C:8]1([C:18]([NH2:23])=[O:20])[CH2:10][CH:9]1[CH2:11][N:12]([CH3:17])[CH3:13]

Participants

4

Reactant 3

HCID 222AmmoniaHCID 313Hydrochloric Acid2×HCID 13218423HCID 13218423, compound

Product 1

HCID 20441518HCID 20441518, compound

Procedure

In a manner similar to that described in Example 1 but hydrolyzing the hydrochloride of 1-orthochlorophenyl 1-ethoxycarbonyl 2-dimethylaminomethyl cyclopropane (Z) and then treating the intermediate acid chloride with ammonia and salifying with hydrochloric acid, there is obtained the product of the formula ##STR17##

Workup

  1. customthere is obtained the product of the formula

Sources & evidence

ORD record
ord-6dd1fcf1d7784b9d9da98e5aecbf3db1
Source dataset
uspto-grants-1984_10
Patent number
US04478836

Reaction notes

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