Triethylamine → HCID 54141135, compound

HRID 1632969Notes

Reaction equation

HRID 1632969 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[CH:6]=[CH:7][C:8](Cl)=[O:9].[CH2:18]([NH:22][C:23]([CH:25]([N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1)[CH3:26])=[O:24])[CH:19]([CH3:21])[CH3:20].C(N(CC)CC)C>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[CH:6]=[CH:7][C:8]([N:30]1[CH2:29][CH2:28][N:27]([CH:25]([C:23]([NH:22][CH2:18][CH:19]([CH3:21])[CH3:20])=[O:24])[CH3:26])[CH2:32][CH2:31]1)=[O:9]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 1120942-Propenoyl chloride, 3-(3,4,5-trimethoxyphenyl)-, (2E)-HCID 20441636HCID 20441636, compound

Product 1

HCID 54141135HCID 54141135, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

14.40 g of 3,4,5-trimethoxycinnamoyl chloride is added to a solution of 9.20 g of 1-[1-(isobutylaminocarbonyl)ethyl]piperazine and 5.70 g of triethylamine in 200 ml of chloroform, and the resulting solution is kept standing at room temperature for 1 hour.

Sources & evidence

ORD record
ord-4df9b36211c54f138e913ba9f2d2954e
Source dataset
uspto-grants-1984_10
Patent number
US04478838

Reaction notes

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