Triethylamine → HCID 53970450, compound

HRID 1632970Notes

Reaction equation

HRID 1632970 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[CH:6]=[CH:7][C:8](Cl)=[O:9].[C:18]([NH:22][C:23]([CH:25]([N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1)[CH3:26])=[O:24])([CH3:21])([CH3:20])[CH3:19].C(N(CC)CC)C>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[CH:6]=[CH:7][C:8]([N:30]1[CH2:29][CH2:28][N:27]([CH:25]([C:23]([NH:22][C:18]([CH3:19])([CH3:21])[CH3:20])=[O:24])[CH3:26])[CH2:32][CH2:31]1)=[O:9]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 1120942-Propenoyl chloride, 3-(3,4,5-trimethoxyphenyl)-, (2E)-HCID 20441635HCID 20441635, compound

Product 1

HCID 53970450HCID 53970450, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

0.78 g of 3,4,5-trimethoxycinnamoyl chloride is added to a solution of 0.50 g of 1-[1-(tert-butylaminocarbonyl)ethyl]piperazine and 0.31 g of triethylamine in 15 ml of chloroform, and the resulting solution is stirred at room temperature for 1 hour.

Sources & evidence

ORD record
ord-9b5a072d4c354033a27aece536f1e74c
Source dataset
uspto-grants-1984_10
Patent number
US04478838

Reaction notes

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