Triethylamine → HCID 70505550, compound

HRID 1632971Notes

Reaction equation

HRID 1632971 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[CH:6]=[CH:7][C:8](Cl)=[O:9].[CH:18]1([NH:24][C:25]([CH:27]([N:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)[CH3:28])=[O:26])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1.C(N(CC)CC)C>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[CH:6]=[CH:7][C:8]([N:32]1[CH2:33][CH2:34][N:29]([CH:27]([C:25]([NH:24][CH:18]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]2)=[O:26])[CH3:28])[CH2:30][CH2:31]1)=[O:9]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 1120942-Propenoyl chloride, 3-(3,4,5-trimethoxyphenyl)-, (2E)-HCID 20441629HCID 20441629, compound

Product 1

HCID 70505550HCID 70505550, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

0.64 g of 3,4,5-trimethoxycinnamoyl chloride is added to a solution of 0.50 g of 1-[1-(cyclohexylaminocarbonyl)ethyl]piperazine and 0.27 g of triethylamine in 15 ml of chloroform, and the resulting solution is kept standing at room temperature for 20 minutes.

Sources & evidence

ORD record
ord-066ab32230f347c881059f74f12f2111
Source dataset
uspto-grants-1984_10
Patent number
US04478838

Reaction notes

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