1-Amino-2-propanol → HCID 11248002, compound

HRID 1633016Notes

Reaction equation

HRID 1633016 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:20]2[CH2:25][CH2:24][S:23](=[O:26])[CH2:22][CH2:21]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][CH2:14][N:15]([CH2:18][CH3:19])[CH2:16][CH3:17])[C:6]=2[N:7]=1.[OH:27][CH:28]([CH3:31])[CH2:29][NH2:30]>>[CH2:16]([N:15]([CH2:18][CH3:19])[CH2:14][CH2:13][S:12][C:8]1[C:6]2[N:7]=[C:2]([NH:30][CH2:29][CH:28]([OH:27])[CH3:31])[N:3]=[C:4]([N:20]3[CH2:25][CH2:24][S:23](=[O:26])[CH2:22][CH2:21]3)[C:5]=2[N:11]=[CH:10][N:9]=1)[CH3:17]

Participants

3

Reactant 2

HCID 41-Amino-2-propanolHCID 13043377HCID 13043377, compound

Product 1

HCID 11248002HCID 11248002, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-8-(2-diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-pyrimido[5,4-d]pyrimidine (melting point: 146°-148° C.) and 2-hydroxypropyl-amine. Resin.

Sources & evidence

ORD record
ord-5120c827b61a47b3b86377d01e4fadc8
Source dataset
uspto-grants-1984_10
Patent number
US04478833

Reaction notes

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