1-Amino-2-propanol → HCID 20441437, compound

HRID 1633025Notes

Reaction equation

HRID 1633025 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:20]2[CH2:25][CH2:24][S:23](=[O:26])[CH2:22][CH2:21]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([NH:12][CH2:13][C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)[C:6]=2[N:7]=1.[NH2:27][CH2:28][CH:29]([OH:31])[CH3:30]>>[OH:31][CH:29]([CH3:30])[CH2:28][NH:27][C:2]1[N:3]=[C:4]([N:20]2[CH2:25][CH2:24][S:23](=[O:26])[CH2:22][CH2:21]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([NH:12][CH2:13][C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)[C:6]=2[N:7]=1

Participants

3

Reactant 2

HCID 41-Amino-2-propanolHCID 12817035HCID 12817035, compound

Product 1

HCID 20441437HCID 20441437, compound

Procedure

This compound was prepared analogous to Example 2 from 2-chloro-4-(1-oxido-thiomorpholino)-8-(3-picolyl-amino)pyrimido[5,4-d]pyrimidine (melting point: 227°-229° C.) and 1-amino-2-propanol.

Sources & evidence

ORD record
ord-b856df544919451198c86c3f29d0626c
Source dataset
uspto-grants-1984_10
Patent number
US04478833

Reaction notes

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