Hydrazine hydrate (1:1) → HCID 12582664, compound

HRID 1633038Notes

Reaction equation

HRID 1633038 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12]([C:14]3[C:15]([CH3:20])=[CH:16][CH:17]=[CH:18][CH:19]=3)=[O:13])[CH2:11][C:4]=2[CH:3]=1.O.[NH2:22][NH2:23]>C(O)C>[NH:22]([C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12]([C:14]3[C:15]([CH3:20])=[CH:16][CH:17]=[CH:18][CH:19]=3)=[O:13])[CH2:11][C:4]=2[CH:3]=1)[NH2:23]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20441568HCID 20441568, compound

Product 1

HCID 12582664HCID 12582664, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

13.0 g of 3-chloro-5,6,7,8-tetrahydro-6-(o-toluoyl)pyrido[4,3-c]pyridazine and 100 cc of hydrazine hydrate are reacted as described in Example 4. Reaction time 2 hours. The bis[3-hydrazino-5,6,7,8-tetrahydro-6-(o-toluoyl)pyrido[4,3-c]pyridazine]trisfumarate has a M.P. of 98°-100° (decomp., from 95% ethanol).

Workup

  1. customReaction time 2 hours

Sources & evidence

ORD record
ord-110d12bd4dd94e41899f9a476b0ca17d
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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