Hydrazine hydrate (1:1) → HCID 12582673, compound

HRID 1633045Notes

Reaction equation

HRID 1633045 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12]([C:14]3[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=3)=[O:13])[CH2:11][C:4]=2[CH:3]=1.O.[NH2:22][NH2:23]>>[NH:22]([C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12]([C:14]3[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=3)=[O:13])[CH2:11][C:4]=2[CH:3]=1)[NH2:23]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20441581HCID 20441581, compound

Product 1

HCID 12582673HCID 12582673, compound

Procedure

12.0 g of 3-chloro-5,6,7,8-tetrahydro-6-(p-toluoyl)pyrido[4,3-c]pyridazine and 50 cc of hydrazine hydrate are stirred at a bath temperature of 100° for 2 hours. The title compound has a M.P. of 207°-210° (decomp., from 95% ethanol).

Sources & evidence

ORD record
ord-80799ae9299f4b738d9e48201ce32776
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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