Hydrazine hydrate (1:1) → HCID 12582679, compound

HRID 1633047Notes

Reaction equation

HRID 1633047 reaction equation
[Br:1][C:2]1[CH:20]=[CH:19][C:5]([C:6]([N:8]2[CH2:18][CH2:17][C:11]3[N:12]=[N:13][C:14](Cl)=[CH:15][C:10]=3[CH2:9]2)=[O:7])=[CH:4][CH:3]=1.O.[NH2:22][NH2:23]>>[Br:1][C:2]1[CH:20]=[CH:19][C:5]([C:6]([N:8]2[CH2:18][CH2:17][C:11]3[N:12]=[N:13][C:14]([NH:22][NH2:23])=[CH:15][C:10]=3[CH2:9]2)=[O:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20441620HCID 20441620, compound

Product 1

HCID 12582679HCID 12582679, compound

Procedure

10.2 g of 6-(p-bromobenzoyl)-3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine and 55 cc of hydrazine hydrate are stirred at a bath temperature of 100° for 2 hours. The title compound has a M.P. of 192°-195° (decomp., from absolute ethanol/methanol 3:1).

Sources & evidence

ORD record
ord-625c0c14a6794d9fbe5c69ea4c90dd97
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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