Hydrazine hydrate (1:1) → HCID 12582676, compound

HRID 1633048Notes

Reaction equation

HRID 1633048 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12](=[O:21])[C:13]3[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=3)[CH2:11][C:4]=2[CH:3]=1.O.[NH2:23][NH2:24]>>[NH:23]([C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12](=[O:21])[C:13]3[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=3)[CH2:11][C:4]=2[CH:3]=1)[NH2:24]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20441556HCID 20441556, compound

Product 1

HCID 12582676HCID 12582676, compound

Procedure

10.5 g of 3-chloro-5,6,7,8-tetrahydro-6-(p-methoxybenzoyl)pyrido[4,3-c]pyridazine and 100 cc of hydrazine hydrate are stirred at a bath temperature of 100° for 1 hour. The title compound has a M.P. of 169°-172° (decomp., from 95% ethanol).

Sources & evidence

ORD record
ord-58d35678c0be48939139e304d85eb205
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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