Hydrazine hydrate (1:1) → HCID 54489213, compound

Participants

Reaction Steps

A solution of 20.3 g of crude oily 3-chloro-5,6,7,8-tetrahydro-6-pyrido[4,3-c]pyridazinecarboxylic acid phenyl ester in 100 cc of hydrazine hydrate is stirred in an oil bath of 100° for 11/2 hours. The reaction solution is concentrated in a vacuum and the residue is divided between 225 cc of chloroform and 25 c of water. The crude title compound is obtained as semicrystalline residue upon concentrating the organic phase in a vacuum.

Provenance & Evidence