Hydrazine hydrate (1:1) → HCID 12582670, compound

HRID 1633067Notes

Reaction equation

HRID 1633067 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12](=[O:21])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[S:19][CH3:20])[CH2:11][C:4]=2[CH:3]=1.O.[NH2:23][NH2:24]>>[NH:23]([C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12](=[O:21])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[S:19][CH3:20])[CH2:11][C:4]=2[CH:3]=1)[NH2:24]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 54342950HCID 54342950, compound

Product 1

HCID 12582670HCID 12582670, compound

Procedure

23.1 g of 3-chloro-5,6,7,8-tetrahydro-6-(o-methylmercaptobenzoyl)pyrido[4,3-c]pyridazine are stirred in 100 cc of hydrazine hydrate at a bath temperature of 100° for 2 hours, and the reaction mixture is worked up as described in Example 17. The gentisinato of the title compound has a M.P. of 172°-175°.

Sources & evidence

ORD record
ord-b12f67fcbc444ca38636215f75627b4c
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

Loading…