1,1-Dichloroethane → (3SR,5RS,6SR)-3-allyl-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((SR)-1-(4-methoxybenzylamino)butan-2-yl)piperidin-2-one

HRID 163313Notes

Reaction equation

HRID 163313 reaction equation
[CH2:1]([CH:2]=[CH2:3])[CH:4]1[C:5](=[O:29])[N:6]([CH:24]([CH:25]=[O:26])[CH2:27][CH3:28])[CH:7]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:8]([c:10]2[cH:11][c:12]([Cl:16])[cH:13][cH:14][cH:15]2)[CH2:9]1.[CH3:30][O:31][c:32]1[cH:33][cH:34][c:35]([CH2:36][NH2:37])[cH:38][cH:39]1.[Cl:40][CH:41]([Cl:42])[CH3:43]>>[CH2:1]([CH:2]=[CH2:3])[CH:4]1[C:5](=[O:29])[N:6]([CH:24]([CH2:25][NH:37][CH2:36][c:35]2[cH:34][cH:33][c:32]([O:31][CH3:30])[cH:39][cH:38]2)[CH2:27][CH3:28])[CH:7]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:8]([c:10]2[cH:11][c:12]([Cl:16])[cH:13][cH:14][cH:15]2)[CH2:9]1

Participants

4

Reactant 3

HCID 63651,1-DichloroethaneHCID 754524-MethoxybenzylamineHCID 768347502-[3-(3-Chlorophenyl)-2-(4-chlorophenyl)-6-oxo-5-prop-2-enylpiperidin-1-yl]butanal

Product 1

HCID 68000804(3SR,5RS,6SR)-3-allyl-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((SR)-1-(4-methoxybenzylamino)butan-2-yl)piperidin-2-one

Sources & evidence

ORD record
ord-3e3ab1342aab4232a79d1a536e54ed95
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…