Methanol → HCID 13362118, compound

HRID 1633153Notes

Reaction equation

HRID 1633153 reaction equation
[OH-].[Li+].[C:3]([C:6]#[C:7][CH2:8][N:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]([CH3:18])=[C:10]1[C:19]1[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=1)([OH:5])=[O:4].[CH3:25]O>>[CH3:25][O:4][C:3]([C:6]#[C:7][CH2:8][N:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]([CH3:18])=[C:10]1[C:19]1[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=1)=[O:5]

Participants

4

Reactant 3

HCID 887MethanolHCID 3939Lithium HydroxideHCID 20268171HCID 20268171, compound

Product 1

HCID 13362118HCID 13362118, compound

Procedure

Treatment of 33 mg of 1-(3-methoxycarbonylprop-2-ynyl)-3-methyl-2-(3-pyridyl)indole in 1 ml of methanol with 0.3 ml of aqueous 1 N lithium hydroxide at room temperature yields 1-(3-carboxyprop-2-ynyl)-3-methyl-2-(3-pyridyl)indole; IR 1720 cm1.

Sources & evidence

ORD record
ord-c6c03d2c3fd54a129e6bd559e878c785
Source dataset
uspto-grants-1984_10
Patent number
US04478842

Reaction notes

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