Benzoylhydrazine → Benzoic acid 2-[(3-amino-5,6-dichloropyrazinyl)methylene]hydrazide

HRID 1633226Notes

Reaction equation

HRID 1633226 reaction equation
[NH2:1][C:2]1[C:3]([CH:10]=O)=[N:4][C:5]([Cl:9])=[C:6]([Cl:8])[N:7]=1.[C:12]([NH:20][NH2:21])(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(O)C>[NH2:1][C:2]1[C:3]([CH:10]=[N:21][NH:20][C:12](=[O:19])[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[N:4][C:5]([Cl:9])=[C:6]([Cl:8])[N:7]=1

Participants

4

Reactant 2

HCID 11955BenzoylhydrazineHCID 133678713-Amino-5,6-dichloropyrazine-2-carbaldehyde

Product 1

HCID 53830705Benzoic acid 2-[(3-amino-5,6-dichloropyrazinyl)methylene]hydrazide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a similar manner, 0.96 gram (0.005 mole) of 3-amino-5,6-dichloropyrazinaldehyde, 0.08 gram (0.005 mole) of benzoic hydrazide and 100 milliliters of ethanol were mixed together and refluxed for 10 minutes to obtain a benzoic acid 2-[(3-amino-5,6-dichloropyrazinyl)methylene]hydrazide product. The product was recovered and recrystallized three times from ethanol to obtain yellow crystals which after drying 2 hours at 100° C. had the following elemental analyses.

Workup

  1. temperaturerefluxed for 10 minutes

Sources & evidence

ORD record
ord-8032e74e4de44409b13e96c9cb0cb43a
Source dataset
uspto-grants-1984_10
Patent number
US04479953

Reaction notes

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