HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54526695, compound → Methyl 1-(6-amino-9H-purin-9-yl)-3-[N-tert-butoxycarbonyl-O-methoxycarbonylmethyl-L-tyrosylamino]-1,3-dideoxy-beta-D-ribofuranuronate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54526695 | HCID 54526695 | — |
| Reactant | N-tert-butoxycarbonyl-O-methoxycarbonylmethyl-L-tyrosine | HCID 59910020 | — |
| Product | Methyl 1-(6-amino-9H-purin-9-yl)-3-[N-tert-butoxycarbonyl-O-methoxycarbonylmethyl-L-tyrosylamino]-1,3-dideoxy-beta-D-ribofuranuronate | HCID 70465257 | 23.7% |
Reaction Steps
Methyl 1-(6-amino-9H-purin-9-yl)-3-[N-tert-butoxycarbonyl-O-methoxycarbonylmethyl-L-tyrosylamino]-1,3-dideoxy-β-D-ribofuranuronate (220 mg) was prepared by reacting methyl 1-(6-amino-9H-purin-9-yl)-3-amino-1,3-dideoxy-β-D-ribofuranuronate (577 mg) prepared in Example 62 with N-tert-butoxycarbonyl-O-methoxycarbonylmethyl-L-tyrosine (520 mg) prepared in Preparation 8 (2) according to a similar manner to that of Example 64, mp. 115°-120° (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04479942 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-0e0e32a6f97b4ee09519a57b2fbf6372 |
| Source note | uspto-grants-1984_10 |