Boc-O-methyl-L-tyrosine → HCID 70465461, compound

Participants

Reaction Steps

1-(6-Amino-9H-purin-9-yl)-3-[N-(N-tert-butoxycarbonyl-O-methyl-L-tyrosyl)-O-methyl-L-tyrosylamino]-1,3-dideoxy-β-D-ribofuranuronic acid (125 mg) was prepared by reacting 1-(6-amino-9H-purin-9-yl)-1,3-dideoxy-3-(O-methyl-L-tyrosylamino)-β-D-ribofuranuronic acid dihydrochloride monohydrate (330 mg) prepared in Example 4 with N-hydroxysuccinimide ester of N-tert-butoxycarbonyl-O-methyl-L-tyrosine (255 mg) according to a similar manner to that of Example 5, mp. 178°-180° C. (dec.).

Provenance & Evidence