HCID 70465461, compound → 3-{2-[2-Amino-3-(4-methoxyphenyl)propanoylamino]-3-(4-methoxyphenyl)propanoylamino}-5-(6-aminopurin-9-yl)-4-hydroxyoxolane-2-carboxylic acid

Participants

Reaction Steps

1-(6-Amino-9H-purin-9-yl)-3-[N-(O-methyl-L-tyrosyl)-O-methyl-L-tyrosylamino]-1,3-dideoxy-β-D-ribofuranuronic acid (46 mg) was prepared by reacting 1-(6-amino-9H-purin-9-yl)-3-[N-(N-tert-butoxycarbonyl-O-methyl-L-tyrosyl)-O-methyl-L-tyrosylamino]-1,3-dideoxy-β-D-ribofuranuronic acid (100 mg) prepared in Example 86 with formic acid according to a similar manner to that of Example 45, mp. 175°-177° C. (dec.).

Provenance & Evidence