反应详情

温度

150 °C

A mixture of 56.0 g (0.28 mole) of 2-aminobenzophenone and 49.6 g (0.31 mole) of 2-chloro-3-nitropyridine was heated in an oil bath with stirring at 150° C. for 45 minutes. After cooling, an 8.7 g portion of the product was dissolved in 45 ml of methylene chloride, hydrogen chloride gas was added for 15 min and 100 ml of hexane was added. After stirring for 20 min, solid was collected and washed twice with 1:3 mixture of methylene chloride to hexanes. After drying in air, 8.2 g (81.6%) product was obtained.

1. temperaturewas heated in an oil bath
2. temperatureAfter cooling
3. stirringAfter stirring for 20 min
4. customsolid was collected
5. washwashed twice with 1:3 mixture of methylene chloride to hexanes
6. customAfter drying in air