Hydrazine hydrate (1:1) → {2-[(3-Aminopropyl)(3-nitropyridin-2-yl)amino]phenyl}(phenyl)methanone

HRID 1633359Notes

Reaction equation

HRID 1633359 reaction equation
[C:1]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N:15]([C:30]1[C:35]([N+:36]([O-:38])=[O:37])=[CH:34][CH:33]=[CH:32][N:31]=1)[CH2:16][CH2:17][CH2:18][N:19]1C(=O)C2C(=CC=CC=2)C1=O)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O.NN>>[NH2:19][CH2:18][CH2:17][CH2:16][N:15]([C:30]1[C:35]([N+:36]([O-:38])=[O:37])=[CH:34][CH:33]=[CH:32][N:31]=1)[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[C:1]([C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[O:8]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 202819432-[3-[(2-Benzoylphenyl)(3-nitro-2-pyridinyl)amino]propyl]-1H-isoindole-1,3-(2H)dione2×

Product 1

HCID 53831951{2-[(3-Aminopropyl)(3-nitropyridin-2-yl)amino]phenyl}(phenyl)methanone

Procedure

Alternately, the product of Example 10, 2-[3-[(2-benzoylphenyl)(3-nitro-2-pyridinyl)amino]propyl]-1H-isoindole-1,3-(2H)dione is reacted with alcoholic hydrazine hydrate and acid to give the title compound.

Sources & evidence

ORD record
ord-881d05627f414fc0a0dcc2dec92d4c39
Source dataset
uspto-grants-1984_10
Patent number
US04480100

Reaction notes

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