Phenylboronic Acid → 4-Fluoro-3-nitro-1,1'-biphenyl

HRID 1633589Notes

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][C:5](I)=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[C:12]1(B(O)O)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]

Participants

Reactant 2

HCID 66827Phenylboronic Acid

HCID 145905821-Fluoro-4-iodo-2-nitrobenzene

Product 1

HCID 106802714-Fluoro-3-nitro-1,1'-biphenyl

Procedure

4-Fluoro-3-nitrobiphenyl (1e) was prepared analogously from 1g and phenylboronic acid.

Sources & evidence

ORD record: ord-0cd02309b7344ccd980d8b35de9e9f54
Source dataset: uspto-grants-2003_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06503925B1

Reaction notes

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