Dichloromethane → 2-Amino-4-chloropyridine-3-carbaldehyde

HRID 163361Notes

Reaction equation

HRID 163361 reaction equation
[Cl:1][c:2]1[c:3]([CH:16]=[O:17])[c:4]([NH:8][C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[n:5][cH:6][cH:7]1.[Cl:25][CH2:26][Cl:27].[OH:18][C:19]([C:20]([F:21])([F:22])[F:23])=[O:24]>>[Cl:1][c:2]1[c:3]([CH:16]=[O:17])[c:4]([NH2:8])[n:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 46204204tert-Butyl 4-chloro-3-formylpyridin-2-ylcarbamate

Product 1

HCID 462035412-Amino-4-chloropyridine-3-carbaldehyde

Sources & evidence

ORD record
ord-8a6fb6bc427f4cca8950eddc3e9f61a6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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