Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1633617Generated: November 1, 2026

Piperidine → 1-(4-Fluoro-phenyl)-5-(6-piperidin-1-yl-hexyloxy)-1H-indole

https://huagongshe.com/reaction/1633617

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant5-(6-Bromo-hexyloxy)-1-(4-fluoro-phenyl)-1H-indoleHCID 11749612—
Product1-(4-Fluoro-phenyl)-5-(6-piperidin-1-yl-hexyloxy)-1H-indoleHCID 18679432—

Reaction Steps

In analogy to example 1.4, 5-(6-Bromo-hexyloxy)-1-(4-fluoro-phenyl)-1H-indole and piperidine were converted to yield 1-(4-Fluoro-phenyl)-5-(6-piperidin-1-yl-hexyloxy) -1H-indole as light brown amorphous, MS: 395 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06503907B2
Source datasetuspto-grants-2003_01
ORD IDord-22cb6047e2f54de6912b398d6cbfa36b
Source noteuspto-grants-2003_01