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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1633625Generated: October 26, 2026

2-(Ethylamino)ethanol → 2-(Ethyl-{4-[1-(4-fluoro-phenyl)-1H-indol-5-yloxy]-but-2-enyl}-amino)-ethanol

https://huagongshe.com/reaction/1633625

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Ethylamino)ethanolHCID 8072—
Reactant5-(4-Bromo-but-2-enyloxy)-1-(4-fluoro-phenyl)-1H-indoleHCID 69548099—
Product2-(Ethyl-{4-[1-(4-fluoro-phenyl)-1H-indol-5-yloxy]-but-2-enyl}-amino)-ethanolHCID 69547848—

Reaction Steps

In analogy to example 3.3, 5-(4-Bromo-but-2-enyloxy)-1-(4-fluoro-phenyl)-1H-indole and 2-ethylaminoethanol were converted to yield 2-(Ethyl-{4-[1-(4-fluoro-phenyl)-1H-indol-5-yloxy]-but-2-enyl}-amino)-ethanol as colorless viscous oil, MS: 369 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06503907B2
Source datasetuspto-grants-2003_01
ORD IDord-09c491add7184adca9ce38499ff18038
Source noteuspto-grants-2003_01