HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargyl alcohol → 3-[1-(4-Fluoro-phenyl)-1H-indol-5-yl]-prop-2-yn-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargyl alcohol | HCID 7859 | — |
| Reactant | Trifluoro-methanesulfonic acid 1-(4-fluoro-phenyl)-1H-indol-5-yl ester | HCID 86585583 | — |
| Product | 3-[1-(4-Fluoro-phenyl)-1H-indol-5-yl]-prop-2-yn-1-ol | HCID 18679472 | — |
Reaction Steps
In analogy to example 5.2, Trifluoro-methanesulfonic acid 1-(4-fluoro-phenyl)-1H-indol -5-yl ester and propargylalcohol were converted to yield 3-[1-(4-Fluoro-phenyl)-1H-indol -5-yl]-prop-2-yn-1-ol as light brown solid, 85-88° C., MS: 265 (M).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06503907B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-8cc8e9a76151448b969b4eb5f7180c45 |
| Source note | uspto-grants-2003_01 |