Sodium Hydroxide → Ethanesulfonic acid, 2,2'-dithiobis-, disodium salt

HRID 1633809Notes

Reaction equation

HRID 1633809 reaction equation
C([S:4][CH2:5][CH2:6][S:7]([OH:10])(=[O:9])=[O:8])(=O)C.[Na].[OH-:12].[Na+:13]>O>[CH2:6]([S:7]([O-:9])(=[O:8])=[O:12])[CH2:5][S:4][S:4][CH2:5][CH2:6][S:7]([O-:10])(=[O:8])=[O:9].[Na+:13].[Na+:13]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 5360545SodiumHCID 116440392-(acetylthio)ethanesulfonic acid

Product 1

HCID 65625Ethanesulfonic acid, 2,2'-dithiobis-, disodium salt

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The ongoing S-acetyl-2-mercaptoethane sulfonic acid, sodium salt (20 g) is dissolved in water and added 1N sodium hydroxide to adjust the pH to 9.0. The reaction mixture is the then stirred while bubbling oxygen for 48 hours. The aqueous portion is then concentrated and crystallized out the product directly. Yield is found to be 80%. The product is characterized by NMR and corroborated the structure with the authentic sample.

Workup

  1. customwhile bubbling oxygen for 48 hours
  2. concentrationThe aqueous portion is then concentrated
  3. customcrystallized out the product directly
  4. customYield

Sources & evidence

ORD record
ord-de48574770104c8b8eae8109c4dbf2b5
Source dataset
uspto-grants-2003_01
Patent number
US06504049B1

Reaction notes

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