HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1633899Generated: October 25, 2026
Potassium Phosphate, Dibasic → HCID 22501863, compound
https://huagongshe.com/reaction/1633899
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Phosphate, Dibasic | HCID 24450 | — |
| Reactant | Monobasic potassium phosphate | HCID 516951 | — |
| Reactant | Ethyl 3-[5-bromomethyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]propionate | HCID 22502293 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 22501863 | HCID 22501863 | — |
Reaction Steps
The crude material from step 2 was dissolved in DMSO (70 mL). Powdered K2HPO4 (18 g, 0.10 mol) and KH2PO4 (7 g, 0.05 mol) were added. The mixture was stirred at 80° C. for 5 hours, diluted with water (500 mL), and extracted with ethyl acetate (3×100 mL). The combined organic extracts were dried (MgSO4), and concentrated. After column chromatography (hexane, ethyl acetate 3:1) 4.8 g of the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06503949B1 |
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| Source dataset | uspto-grants-2003_01 |
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| ORD ID | ord-5af73a200d4a499293ff41a737d22d21 |
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| Source note | uspto-grants-2003_01 |
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