HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 54232827, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 1,4-Dioxa-8-azaspiro(4.5)decane | HCID 67435 | — |
| Reactant | 2-Chlorosulfonylmethyl-3-methyl-butyric acid tert-butyl ester | HCID 21259094 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 54232827 | HCID 54232827 | — |
Reaction Steps
2-Chlorosulfonylmethyl-3-methylbutyric acid tert-butyl ester, dichloromethane (60 ml), triethylamine (82 ml), and 1,4-dioxa-8-aza-spiro[4.5]decane(1.59 g) were reacted as above. Purification by flash chromatography (eluent 50% hexane/diethyl ether) yielded the title compound as a green gum (1.57 g). Rf 0.35 (50% hexane/diethyl ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506764B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-d614161e78bd4a04a31474cd5f2fe716 |
| Source note | uspto-grants-2003_01 |