HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Amino-4,4-dimethyl-2h,4h-isoquinoline-1,3-dione → 4,4-dimethyl-7-acetamino-2H,4H-isoquinoline-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Amino-4,4-dimethyl-2h,4h-isoquinoline-1,3-dione | HCID 23502914 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 4,4-dimethyl-7-acetamino-2H,4H-isoquinoline-1,3-dione | HCID 13558156 | 171.3% |
Reaction Steps
The above amine (1.5 g, 7.35 mmol) was stirred in acetic anhydride (9 mL) at room temperature for 3 h, then poured on to ice. The precipitate was filtered, washed with water and dried to give 7-acetamido-4,4-dimethyl-2H,4H-isoquinoline-1,3-dione (1.55 g, 86%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506769B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-7117a601929b4bd384c4a312cbb6b153 |
| Source note | uspto-grants-2003_01 |