HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-amino-2-phenylpiperidine-1-carboxylate → (2S,3S)-1-tert-Butoxycarbonyl-3-(2-Methoxy-5-(1,1,2,2,2-pentafluoroethyl)benzyl)amino2-phenylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-amino-2-phenylpiperidine-1-carboxylate | HCID 10214733 | — |
| Reactant | 2-Methoxy-5-(1,1,2,2,2-pentafluoroethyl)benzaldehyde | HCID 18677612 | — |
| Reactant | HCID 70001814 | HCID 70001814 | — |
| Product | (2S,3S)-1-tert-Butoxycarbonyl-3-(2-Methoxy-5-(1,1,2,2,2-pentafluoroethyl)benzyl)amino2-phenylpiperidine | HCID 86757655 | — |
Reaction Steps
This Compound was prepared from Compound 12 and Compound 40 in the same manner of Compound 26. This was employed in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506775B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-52a65bf15e6d490e9911b3627ff58b04 |
| Source note | uspto-grants-2003_01 |