Potassium Carbonate → HCID 59032953, compound

HRID 1634723Notes

Reaction equation

HRID 1634723 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][C:5](=[O:11])[NH:6]2.S(C1C=CC([N+]([O-])=O)=CC=1)(O[CH2:16][C@H:17]1[O:19][CH2:18]1)(=O)=O.C(=O)([O-])[O-].[K+].[K+]>>[O:19]1[CH2:18][C@H:17]1[CH2:16][O:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][C:5](=[O:11])[NH:6]2

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 5909114-Hydroxyindolin-2-oneHCID 10868995(S)-(+)-Glycidyl-4-nitrobenzoate

Product 1

HCID 59032953HCID 59032953, compoundYield 21.8%

Procedure

Prepared from 4-hydroxy-2-oxindole (1.1 g, 7.38 mmol), (S)-glycidyl nosylate (1.91 g, 7.38 mmol) and potassium carbonate (1.1 g, 8 mmol) according to the procedure used for Intermediate 1 to give 0.33 g product as a white solid.

Sources & evidence

ORD record
ord-0855beb1f02c4ce1abe3a95bd06fe56a
Source dataset
uspto-grants-2003_01
Patent number
US06506901B2

Reaction notes

Loading…