Hydrochloric Acid → HCID 18678400, compound

Participants

Reaction Conditions

Reaction Steps

A solution of methyl 4-(4-(dimethoxymethyl)piperidinyl)benzoate(5.6 g, 18.2 mol) was in methanol (50 mL) 1N sodium hydroxide (27 mL) was heated at 80° C. for 5 hours. The reaction was neutralized with 1N HCl (27 ml) and concentrated in vacuo. Additional methanol was added to the residue which was filtered (0.5 micron filter) and evaporated to give 5.0 g of the product.

Provenance & Evidence