HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18678703, compound → (2S)-1-(3-Bromo-9H-carbazol-4-yloxy)-3-{[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylmethyl]-amino}-propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18678703 | HCID 18678703 | — |
| Reactant | 3-bromo-4-[(2S)-oxiranylmethoxy]-9H-carbazole | HCID 59032961 | — |
| Product | (2S)-1-(3-Bromo-9H-carbazol-4-yloxy)-3-{[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylmethyl]-amino}-propan-2-ol | HCID 10121505 | 100.9% |
Reaction Steps
Prepared from 3-bromo-4-[(2S)-oxiranylmethoxy]-9H-carbazole (0.083 g, 0.26 mmol) and (4-aminomethyl-1-piperidinyl) 4-methoxybenzenesulfonamide (0.142 g, 0.5 mmol) according to procedure used for Example 2 to give 0.079 g of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506901B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-4ca4c42f17df4810b59572e70797e24c |
| Source note | uspto-grants-2003_01 |