反应详情

N-(4-{[4-(aminomethyl)-1-piperidinyl]sulfonyl}phenyl)-N′-(2,5-difluorobenzyl)urea formate (0.827 g, 1.72 mmol) was reacted with t-butyl(diphenyl)silyl 3-chloro-4-[(2S)oxiranylmethoxy]phenyl ether (0.516 9,1.17 mmol) according to example 37 to give the title compound (0.15 g, 0.23 mmol).