HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → 2,5-Difluoro-N-(1-methylethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 2,5-Difluorobenzoic acid | HCID 76339 | — |
| Product | 2,5-Difluoro-N-(1-methylethyl)benzamide | HCID 17683299 | — |
Reaction Steps
The title compound was prepared from 2,5-difluorobenzoic acid (10 g, 63.2 mmol), carbonyldiimidazole (9.57 g, 61 mmol) and isopropyl amine (5.15 mL, 60.5 mmol) according to the procedure used for example 84 (Step A) to give near quantitative yield of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506901B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-1e62e3fac67c4e4bbaed1647e65dc3a1 |
| Source note | uspto-grants-2003_01 |